Central Muscle Relaxants (C.M.R.)
The drugs are:
C Carisoprodol, Chlorzoxazone, Chlormezanone
M Mephenesin, Meprobamate, Methocarbamol
R Receptor acting drugs increasing GABAergic transmission:
· Benzodiazepines (act on BZD receptors linked with GABAA receptors)
· Baclofen (act on GABAB receptors)
Their clinical uses are:
C CNS disorders associated with spasticity
e.g. hemiplegia, paraplegia, multiple sclerosis and cerebral palsy
M Manipulations in Orthopaedics
e.g. setting of fracture and dislocations
R Relieving muscle spasms
e.g. after trauma, tetanus, torticollis and tension & anxiety
Muscle spasm is general problem between men and women.It may appear due to hard physical work .It may affect your sleep and affect your regular actives.to treat this problem,Methocarbamol is popular muscle relaxant introduced to get resolve from this pain.
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