CHOLINERGIC DRUGS
Acetylcholine (A C h) is the prototype drug.
A Action is nonspecific &
C Cholinesterase enzyme quickly degrades it,
h hence not used clinically.
ANTICHOLINERGIC DRUGS
Atropine is the prototype drug.
(Atropine is obtained from ATROPA belladonna or DHATURA stramonium.)
Clinical uses of Atropine
A As mydriatic-cycloplegic → used topically in refraction testing, fundoscopy and giving rest to
the inflamed eye.
T Traveller’s diarrhea
R Rapid onset mushroom poisoning
O Organophosphorous poisoning
P Preanaesthetic medication
A Arrythmias (brady-arrhythmias)
Adverse effects of Atropine
D Dry mouth → Difficulty in swallowing and speaking
H Hot dry skin & Hypotension
A Accomodation paralysis → blurring of near vision
T Tachycardia
U Urinary retention and (faecal retention) constipation
R Respiratory depression
A Ataxia & Acute congestive glaucoma may precipitate
that's great appreciable :)
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